The Developmental Epigenetics Department is seeking a highly motivated Postdoctoral Researcher with expertise in germline and early embryonic development to join our interdisciplinary team.

Our laboratory has uncovered a novel mechanism of epigenetic inheritance, demonstrating that parents transmit not only genetic but also epigenetic information to their offspring via histone post-translational modifications. We have shown that the repressive marks H3K27me3 and H3K9me3 are retained on post-meiotic oocytes and transmitted intergenerationally from the germline to the embryo. This work revealed an unexpected role for germline-inherited histone modifications in regulating gene expression in the early embryo.

Our department is broadly focused on the epigenetic mechanisms underlying:

• the formation of functional gametes

• the establishment of the zygotic epigenome at fertilization

• the influence of environmental factors on heritable epigenetic states

We work with both Drosophila and mammalian model systems.

Qualifications:

• PhD in Developmental Biology, Genetics, Molecular Biology, or a related field

• Strong expertise in germline and early embryonic development

• Experience in epigenetics, particularly chromatin biology or histone modifications

• A collaborative spirit and enthusiasm for interdisciplinary research

If you’re excited about exploring how epigenetic information is inherited and shapes early development, we would love to hear from you.