Specific field of research
Biochemistry, Structural Biology, Chemical Biology, Biophysics
Short description of the group/project/topic of research
Research projects in the Raunser lab focus on important biological questions concerning the structural organization of muscles, cytoskeletal proteins and bacterial toxin complexes. Our ultimate goal is to understand the mechanisms and structure-function relationship underlying these processes in health and disease in molecular detail. To this end, we employ single particle electron cryo-microscopy (cryo-EM), cryogenic focused ion beam milling (cryo-FIB), electron cryo-tomography (cryo-ET), X-ray crystallography, biochemical and biophysical methods and cell biology.
There are several projects available in our lab for talented and outstanding young researchers who are eager to apply cryo-FIB and cryo-ET to look deeper into human hearts in order to visualize and understand cellular components that have never been seen before. A special focus will be on understanding the molecular underpinnings of human cardiomyopathies.
Additional information
We seek highly motivated, self-driven and creative thinkers who are prepared to take risks in defining and addressing important scientific problems, and who use quantitative experimental, computational and/or technical approaches in their work.
Ideal candidates should hold an excellent PhD in structural biology, biophysics, physics or in an equivalent area with previous experience in single particle cryo-EM or cryo-ET. Strong written and oral communication skills in English are required.
Our dynamic research environment, distinct culture, and diverse community foster collaboration and excellence in every corner of science. We offer an extensive range of benefits and resources such as:
- access to state-of-the-art research facilities
- opportunities to collaborate on cutting-edge research
- an international and exciting working atmosphere
- an integrated training program that includes lectures, advanced scientific workshops, complementary skill courses and opportunities for career development
- a mentoring program to guide and promote young scientists
Link to PI’s webpage
https://www.mpi-dortmund.mpg.de/research-groups/raunser