We are seeking a highly motivated postdoctoral fellow to lead an ambitious program aiming at unraveling the role of viruses in the evolutionary transition to multicellularity, using brown algae as model organisms.

Genome sequencing is increasingly uncovering integrated viral DNA within the genomes of various eukaryotes. Some eukaryotic viruses are lysogenic, and their persistent integration into the host genome is a fundamental part of their life cycle. This is notably seen in phaeoviruses, which infect brown algae and are distinguished by their large genomes, often spanning several hundred kilobases and containing hundreds of genes. The life cycle of these 'giant' phaeoviruses is intricately coordinated with the reproductive cycle of their host: viral activation is triggered during specific reproductive stages of the host, and mature viral particles exploit the host’s reproductive structures for replication and dispersal. There is also evidence that brown algae have frequently co-opted viral domains, some of which can be found in key developmental genes, suggesting both the host and the virus have evolved strategies to maintain a stable association. Despite this clear relationship, our understanding of the mechanisms underlying the association between virus and host, co-option of viral domains and viral genes and the potential role of virus-derived genes in multicellular development remains elusive. 

The postdoc will use classical and reverse genetics, microscopy, molecular and cell biology approaches combined with genomics to understand the mechanisms underlying the association between virus and brown algae, in particular how phaeovirus may shape evolution of multicellularity in the brown algae. 

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We are looking for a highly motivated postdoctoral researcher, with a strong background in developmental and/or cell biology. Knowledge and demonstrated experience in genetics, molecular biology, mutant analysis, reverse genetics and data analysis is necessary. Experience in computational biology is a plus. Candidates should have an advanced academic degree (Ph.D.) in biology, genomics or a related field and must have published previously in peer-reviewed journals. The candidate should be able to work independently and also have excellent team working skills. The position further requires organizational qualifications and the ability to communicate effectively with internal and external collaborators. An excellent written and oral command of English is essential.