Our research:

Join a world leader in mass spectrometry-based proteomics. The Department of Proteomics and Signal Transduction at the Max Planck Institute of Biochemistry (MPIB), led by Prof. Dr. Matthias Mann, has shaped the field for over two decades — from pioneering computational proteomics to building some of the most advanced analytical workflows in the world. Our work spans from fundamental technology development to direct biomedical application, and our methods are used by laboratories and clinical groups globally.

We operate at the frontier of what mass spectrometry can achieve: single-cell proteomics, deep visual proteomics with spatial resolution, and high-throughput clinical workflows — powered by a world-class instrument platform featuring the newest generation of Orbitrap-Astral, timsTOF, and SCIEX systems. Our computational environment includes the AlphaX open-source software ecosystem and active development of next-generation algorithms, including approaches to the dark proteome.

What you will do:

You will join a diverse, international team and pursue an independent research program at the intersection of MS technology development and biomedical application. Depending on your interests and strengths, your work will include:

• Developing next-generation proteomics workflows that push the boundaries of depth, throughput, and sensitivity across diverse biological matrices.
• Pioneering new analytical strategies – including multi-omics approaches such as MS-based lipidomics – and applying them to major biomedical questions.
• Contributing to Parkinson's disease research as part of a newly established, multi-year international network, working with human biomaterials including brain tissue, cerebrospinal fluid, blood, and skin.
• Collaborating with instrument manufacturers and our institute core facility to evaluate emerging MS technologies.

We are looking for someone who wants to make a real scientific impact — not just run samples but shape the direction of the field.

Requirements:

• PhD in chemistry, biochemistry, biology, or a related field.
• Strong experience in mass spectrometry-based proteomics or a closely related analytical field.
• A track record of scientific independence, creativity, and ambition – demonstrated through publications, method development, or technical innovation
• Interest in translational research and willingness to tackle complex biological questions.
• Excellent communications skills in English

Our offer:

The successful applicant will become part of a renowned group in a dynamic international research environment, known for its collaborative and collegial scientific atmosphere. You will have access to one of the best-equipped MS laboratories in the world, a strong computational infrastructure, and an extensive network of academic and industry collaborators. The position is available from June 1, 2026. Salary follows the German public pay scale (TVöD), depending on experience and qualification. The Max Planck Society strives for gender equality and diversity and encourages applications from all backgrounds. Applications from severely disabled persons are expressly welcome. For further information about MPIB, please see http://www.biochem.mpg.de.